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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
10.61
Human Site:
S500
Identified Species:
14.58
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S500
K
D
G
L
K
E
F
S
L
S
I
V
H
S
W
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S500
K
D
G
L
K
E
F
S
L
S
I
V
H
S
W
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
S498
K
K
G
L
K
E
F
S
L
S
I
V
H
S
W
Dog
Lupus familis
XP_532459
1267
140567
F484
M
K
D
G
L
K
E
F
S
L
N
V
V
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
S501
G
L
R
E
F
S
L
S
T
V
H
S
Q
E
K
Rat
Rattus norvegicus
P46462
806
89330
D107
I
S
I
Q
P
C
P
D
V
K
Y
G
K
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
S465
G
M
K
E
F
Y
L
S
A
V
Q
P
P
E
P
Chicken
Gallus gallus
XP_418655
1290
143066
H508
L
S
V
V
D
N
M
H
T
E
E
D
K
S
E
Frog
Xenopus laevis
P23787
805
89193
P106
V
I
S
I
Q
P
C
P
D
V
K
Y
G
K
R
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
D107
I
S
I
Q
P
C
P
D
V
K
Y
G
K
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
C102
D
V
V
S
V
Q
S
C
P
D
V
K
Y
G
K
Honey Bee
Apis mellifera
XP_397107
1069
120490
P370
D
R
T
E
I
S
V
P
S
S
L
E
L
F
S
Nematode Worm
Caenorhab. elegans
P54812
810
89622
A111
D
V
V
S
I
S
S
A
Q
L
E
Y
G
K
R
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
T654
N
H
D
V
K
E
S
T
K
E
S
Y
F
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
G116
Q
C
P
D
V
K
Y
G
N
R
V
H
I
L
P
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
G344
K
D
V
P
T
K
S
G
D
Q
Y
S
K
L
L
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
I550
P
P
F
A
R
E
V
I
L
Q
H
V
R
T
P
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
0
N.A.
6.6
6.6
0
0
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
100
93.3
13.3
N.A.
6.6
6.6
N.A.
6.6
13.3
13.3
6.6
N.A.
20
13.3
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
0
0
0
6
6
0
0
0
0
0
0
% A
% Cys:
0
6
0
0
0
12
6
6
0
0
0
0
0
0
0
% C
% Asp:
18
18
12
6
6
0
0
12
12
6
0
6
0
0
0
% D
% Glu:
0
0
0
18
0
30
6
0
0
12
12
6
0
12
6
% E
% Phe:
0
0
6
0
12
0
18
6
0
0
0
0
6
6
0
% F
% Gly:
12
0
18
6
0
0
0
12
0
0
0
12
12
6
0
% G
% His:
0
6
0
0
0
0
0
6
0
0
12
6
18
6
0
% H
% Ile:
12
6
12
6
12
0
0
6
0
0
18
0
6
0
12
% I
% Lys:
24
12
6
0
24
18
0
0
6
12
6
6
24
12
12
% K
% Leu:
6
6
0
18
6
0
12
0
24
12
6
0
6
18
12
% L
% Met:
6
6
0
0
0
0
6
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
6
0
0
6
0
6
0
0
0
0
% N
% Pro:
6
6
6
6
12
6
12
12
6
0
0
6
6
0
18
% P
% Gln:
6
0
0
12
6
6
0
0
6
12
6
0
6
0
0
% Q
% Arg:
0
6
6
0
6
0
0
0
0
6
0
0
6
12
12
% R
% Ser:
0
18
6
12
0
18
24
30
12
24
6
12
0
24
12
% S
% Thr:
0
0
6
0
6
0
0
6
12
0
0
0
0
6
0
% T
% Val:
6
12
24
12
12
0
12
0
12
18
12
30
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
18
% W
% Tyr:
0
0
0
0
0
6
6
0
0
0
18
18
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _